Post-Doctoral Fellow in Oncology (H/F)
We are a human-scale, international, and independent pharmaceutical group governed by a Foundation. Our unique model makes us proud and, more importantly, enables us to fully serve our mission: "committed to therapeutic progress for the benefit of patients."
As a global leader in cardiology, we aim to become a focused and innovative player in oncology by 2030, targeting hard-to-treat cancers and dedicating more than 70% of our R&D budget to this goal.
Who are we? 22,000 passionate individuals from over 50 nationalities, driven by an entrepreneurial spirit. Every day, we move forward with and for patients, with and for our teams, motivated by the desire to care, to dare, to grow, and to commit to being useful to those in need.
Come and experience and contribute to our commitment #MovedByYou.
Post-Doctoral Fellow in Oncology
Are you a dynamic and innovative researcher passionate about advancing brain cancer treatment? We are seeking a post-doctoral fellow to join our oncology drug discovery team, focusing on Glioblastoma (GBM). This is a unique opportunity to play a crucial role in exploring DNA Damage Response (DDR) pathways in GBM, understanding its role in tumor progression/resistance and ultimately contributing to the development of novel therapeutic strategies.
Why Join Us?
- Impactful Research: Glioblastoma (GBM) is the most common, aggressive, and heterogeneous malignant brain tumor with a very high unmet need. DDR pathways are often altered and dysregulated in GBM tumors, contributing to resistance to conventional therapies. This highlights a significant medical need and an area ripe for innovative research.
- Innovative Environment: Lead efforts to dissect DNA damage and repair pathways in GBM, implementing new imaging technologies to measure DNA breaks and explore DDR in 2D & 3D GBM cellular models. Make a significant impact in oncology by addressing critical unmet medical needs.
- Collaborative Team: Work alongside multidisciplinary teams to ensure alignment and integration of research efforts with broader organizational goals.
Responsibilities :
- Design and implement relevant studies to explore DDR in GBM cellular models.
- Develop and implement new imaging technologies to measure DNA damage and associated DDR pathways, including biomarkers.
- Analyze data and propose the next steps in research.
- Collaborate with multidisciplinary teams (e.g., In Vitro Pharmacology, US Research, Integrative Molecular Pharmacology, Translational Medicine).
- Follow literature in the field of DDR and GBM.
- Support associated projects with new findings. Present research findings at internal meetings.
- Prepare and publish scientific manuscripts.
Profile :
- PhD in Oncology.
- Experience in cancer cell biology, biochemistry, and pharmacology.
- Proven research record, including conceptual work that resulted in a first-author publication (or in the process of publishing).
- Expertise in imaging technologies, 2D and 3D cultures, and silencing technologies.
- Experience in DDR pathways.
- Experience in brain tumors is a plus.
- Ability to collaborate in an integrated, multi-disciplinary, and international team environment with a willingness to share knowledge.
- Autonomous, proactive, rigorous, innovative, and committed team player.
- Mastery of oral and written English; French is a plus.
We are committed to equal opportunities and developing talents in all their diversity. We value both experience and the desire to engage daily in contributing to therapeutic progress for the benefit of patients. If this offer resonates with you, seize this opportunity to meet us!