Sr. Director, Enterprise Program Management Office (EPMO)

About Servier

Servier in the U.S. is a Boston-based, commercial-stage biopharmaceutical company launched by Servier Group in 2018. As a privately held organization, Servier is uniquely positioned to advance cutting-edge science, tackle underserved therapeutic areas and make patients the focus of every strategic decision.

Role Summary

The Senior Director, Enterprise Program Management Office (EPMO) is a senior enterprise leader responsible for establishing and scaling a best-in-class program and portfolio management capability that connects strategy to execution across Servier U.S. This role defines and drives the enterprise execution framework. This includes governance, standards, tools, and portfolio visibility, enabling consistent, transparent, and accountable delivery of strategic priorities.

Operating within the Enterprise Innovation Office (EIO), the Senior Director serves as the owner of the enterprise initiative operating model and portfolio governance, providing leadership, oversight, and enablement to program delivery teams. This role plays a critical part in advancing the company’s growth agenda, with accountability for U.S. post-merger integration (PMI) and coordination of enterprise-wide operational improvement initiatives aligned with global priorities.

The role requires strong leadership in navigating ambiguity, influencing senior stakeholders, and driving cross-functional alignment. Success in this position depends on the ability to embed disciplined ways of working while fostering agility and innovation within a highly regulated pharmaceutical environment.

Primary Responsibilities

Enterprise Execution Framework & Portfolio Enablement

• Define and maintain the end-to-end enterprise initiative lifecycle (intake, scoping, planning, governance, reporting, and closeout) to ensure strategic work is executed with clarity and discipline.
• Establish engagement models and intake thresholds for when initiatives are resourced through the EPMO and/or assigned to delivery owners (e.g., the Director, EPM), ensuring consistent ways of working across teams.
• Partner with Executive Leadership and functional leaders (Commercial, R&D, Medical, Industry, HR, IT/DDIS, Finance, etc.) to align prioritization, clarify decision rights, and manage cross-initiative dependencies.
• Set and in some instances lead enterprise governance, including steering committees and escalation frameworks, ensuring timely, transparent, and well-documented decision-making
• Provide functional leadership for enterprise program management, including direct people leadership of the Director, Enterprise Program Management (EPM) and oversight of program/project management resources as one pillar within the broader EPMO remit.

Post Merger-Integration and Enterprise Project Leadership

• Lead the U.S. post-merger integration (PMI) strategy and execution, ensuring alignment with deal objectives and value realization targets
• Define integration priorities, timelines, and success metrics; drive execution across cross-functional teams
• Serve as a central coordination point for enterprise initiatives, ensuring alignment across business units and with global strategy
• Oversee strategic, non-therapeutic enterprise programs (e.g., SPOT) in alignment with Servier Group priorities
• Guide high-impact operational improvement initiatives that advance innovation, efficiency, and scalability

Enterprise Governance, Portfolio Visibility & Decision Support

• Design and implement governance structures (steering committees, escalation paths, decision forums) to enable timely decisions and maintain accountability across initiatives managed by the EIO.
• Build and maintain an enterprise view of major initiatives (portfolio/inventory), including status, risks, resource needs, interdependencies, and value/outcome tracking.
• Define and track EPMO KPIs to measure progress, outcomes, and change adoption; provide transparent, data-driven reporting for senior leadership.
• Define and reinforce clear roles, responsibilities, and engagement models to ensure effective interaction with the EPMO
• Establish and evolve enterprise program management standards, methodologies, and tools to support a range of delivery models (e.g., Agile, hybrid, innovation-led)
• Own and optimize the program management technology ecosystem to enable collaboration, transparency, and knowledge sharing
• Build enterprise capabilities through training, coaching, and thought leadership, strengthening execution discipline and stakeholder engagement
• Foster a culture of continuous improvement, embedding learning, adaptability, and an innovation-oriented PMO mindset
• Provide training, coaching, and enablement to project teams and workstream leads to improve delivery discipline, risk management, and stakeholder engagement across the enterprise.
• Promote learning from successes and failures; help embed an “innovation PMO” mindset that supports experimentation and iterative delivery where appropriate.

Organizational Change, Communications & Stakeholder Leadership

• Lead stakeholder alignment across functions and levels; facilitate workshops, working sessions, and decision meetings to drive clarity and execution.
• Develop and execute program communications (status updates, risks/issues, decisions required) with messaging tailored to executive and operational audiences.
• Partner with change enablement and functional leaders to support adoption planning (training, readiness, reinforcement) and to monitor adoption and outcomes post-implementation.
• Influence senior leaders and cross-functional stakeholders in a matrixed global environment.

Resourcing, Vendor & Partner Management

• Assess enterprise initiative demand and resourcing needs; build capacity plans for program/project management talent (including internal PMs and external partners) in collaboration with functional leaders.
• Establish standards and governance for vendor/consulting partner engagement (e.g., integration support, PM tooling, methodology development) and ensure deliverables meet quality, timelines, and value expectations.
• Support budget planning and forecasting for enterprise programs and EPMO operations in partnership with Finance and Procurement.

Regulatory & Compliance Alignment

• Ensure enterprise initiatives are executed with appropriate governance and documentation to support quality and compliance expectations in a regulated life sciences environment.
• Partner with Quality, Regulatory, Privacy/Security, and other control functions (as applicable) to identify and mitigate risks during transformation, system implementation, and integration activities.

Education and Required Skills

• Bachelor’s degree required; advanced degree (MBA, MS, PharmD, or PhD) preferred.
• PMP, PgMP, or equivalent program/portfolio management certification strongly preferred.
• 12+ years of progressive experience in enterprise program, portfolio, or transformation management; life sciences/pharmaceutical experience strongly preferred.
• Proven experience leading complex, cross-functional transformation and/or integration programs; ability to operate effectively in ambiguity and evolving environments.
• Deep program management expertise including governance design, dependency management, risk/issue management, financial tracking, benefits realization, and executive reporting.
• Strong understanding of modern delivery and innovation methods (Agile, Lean Startup, Design Thinking) and when to apply them appropriately.
• Executive-level communication skills (written and verbal) with demonstrated ability to influence senior stakeholders in a matrixed organization.
• Strong facilitation, conflict resolution, negotiation, influence and change management capabilities.
• Experience building and leading PMO/EPMO capabilities, including developing tools/templates, training, and coaching project teams.
• Vendor/partner management experience, including oversight of consulting firms and third-party providers.

Travel and Location

• Boston, MA: hybrid work schedule of 2-3 days onsite in our Seaport location

Servier’s Commitment

Servier is committed to modeling diversity, equity, and inclusion within the industry. We are dedicated to fostering an environment that maintains equitable treatment for all and we welcome applicants who are passionate, committed, and innovative individuals. We encourage candidates to apply to our open roles as we are always willing to consider experiences and skills beyond what is listed in the job description.

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.

Salary Range

The salary range for this role is $223-$273k. An employee’s pay position within the salary range will be based on several factors including, but not limited to, relevant education, qualifications, certifications, experience, skills, geographic location, performance, and business or organizational needs. We may ultimately pay more or less than the posted range, and the range may be modified in the future. Employees in this position are also eligible for Short-Term and Long-Term incentive programs. Servier also offers a competitive and comprehensive benefits package that includes benefits such as medical, dental, vision, flexible time off (Servier provides unlimited sick time and flex time, and does not accrue time off), 401(k), life and disability insurance, recognition programs among other great benefits (all benefits are subject to eligibility requirements).  For more information on our benefits, please visit this link.